Preparation and purification of the topical local anaesthetic benzocaine, ethyl-4-aminobenzoate, via two alternative routes: 1. via esterification of 4-aminobenzoic acid with ethanol and a strong acid catalyst; 2. via reduction of ethyl-4-nitrobenzoate using zinc dust in strong acid; - either route takes "typical" 6th form student ca. 2 - 2.5 hours to complete. Student instruction sheet and Technicians apparatus and chemicals list for each route.

Last modified

• 10/19/2024

Contributors

• Hoare, Peter

Contributor type

• creator

Subject

• Reduction
• Organic
• Esterification
• Benzocaine
• Solvent extraction
• SFSOER
• Reflux
• UKOER
• Recrystallisation
• Chemistry
• Outreach

Publisher

• The University of Hull

Identifier

• hull:3855

Related item publisher

• The University of Hull

Resource type general

• Learning materials